The fatal crash happened in the westbound lane of South Market Street/Route 114 at the intersection with the ramps to Route 15 at 12:30 p.m., Schreffler explained.
The motorcycle rider died at the scene, according to PennDOT citing police.
The Rt 114 was closed between Gettysburg Pike and the intersection of Bumble Bee Hollow Road/Kim Acres Drive, according to Upper Allen Township Police, and the area was expected to reopen at 5:30 p.m. but ended up reopening at 4:13 p.m., Schreffler said.
Pennsylvania State Police remain on the scene doing reconstruction and will continue to investigate this deadly crash.
The public is to avoid the area.
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